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KCNF1

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]
Protein class

Plasma proteins, Transporters, Voltage-gated ion channels

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Oligodendrocyte precursor cells, Extravillous trophoblasts, Excitatory neurons, Inhibitory neurons, Syncytiotrophoblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (A549, MCF7, T-47d)

Interaction

Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1.

Molecular function

Ion channel, Potassium channel, Voltage-gated channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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