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KCNJ4

Protein class

FDA approved drug targets, Transporters, Voltage-gated ion channels

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons, Horizontal cells, Muller glia cells, Microglial cells, Cardiomyocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (SCLC-21H)

Interaction

Homomultimeric and heteromultimeric association with KCNJ2 and KCNJ12. Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking (By similarity). Interacts with TAX1BP3. TAX1BP3 competes with LIN7 family members for KCNJ4 binding.

Molecular function

Ion channel, Voltage-gated channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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