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KCNU1

Kcnu1 (Potassium Calcium-Activated Channel Subfamily U Member 1) is a Protein Coding gene. This gene encodes a member of the potassium channel family of proteins. The encoded voltage-gated ion channel allows the outward flow of potassium ions during plasma membrane hyperpolarization in sperm. Diseases associated with Kcnu1 include Lymph Node Carcinoma and Severe Congenital Neutropenia 6.
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Early spermatids, Late spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (HDLM-2)

Interaction

Homotetramer; which constitutes the calcium-activated potassium channel. May interact with LRRC52; this interaction may change channel gating properties, such as shifting gating to more negative potentials at a given pH.

Molecular function

Ion channel, Potassium channel, Voltage-gated channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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