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KLK11
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
Protein class
Cancer-related genes, Enzymes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Late spermatids, Prostatic glandular cells, Club cells, Suprabasal keratinocytes, Urothelial cells, Squamous epithelial cells, Basal prostatic cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (EFO-21, HaCaT)
Molecular function
Hydrolase, Protease, Serine protease
More Types Infomation
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- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, IP
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG3
- Application: WB, IF, IHC, IP
- Recombinant Rat Anti-KLK11 Antibody (CBL624) (NEUT-1637CQ)
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- Species Reactivity: Human
- Type: IgG2a
- Application: Neut
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For Research Use Only. Not For Clinical Use.