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KRT20

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Group enriched (Paneth cells, Distal enterocytes, Proximal enterocytes, Intestinal goblet cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (NB-4)

Interaction

Heterotetramer of two type I and two type II keratins. Associates with KRT8.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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