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KRT23

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Syncytiotrophoblasts, Prostatic glandular cells, Urothelial cells, Basal prostatic cells, Cytotrophoblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (HBEC3-KT, Hep G2, SuSa, T-47d)

Interaction

Heterotetramer of two type I and two type II keratins.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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