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LAMA1

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components
Protein class

Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Distal enterocytes, Astrocytes, Granulosa cells, Proximal enterocytes, Intestinal goblet cells, Paneth cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, ASC diff, BEWO, hTEC/SVTERT24-B, SK-MEL-30)

Interaction

Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-1 is a subunit of laminin-1 (laminin-111 or EHS laminin) and laminin-3 (laminin-121 or S-laminin).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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