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LANCL1

This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Protein class

Enzymes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Inhibitory neurons, Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with the C-terminal of STOM (PubMed:9512664). Interacts with the EPS8 SH3 domain. Interaction with EPS8 is inhibited by glutathione binding (PubMed:19528316). (Microbial infection) Interacts with P. falciparum SBP1.

Molecular function

Transferase

More Types Infomation

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