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LBX1

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by RefSeq, Jul 2008]
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Skeletal myocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (HEK93, RH-30, SCLC-21H)

Interaction

Interacts with SKOR1 which acts as a transcriptional corepressor.

Molecular function

Developmental protein, DNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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