Intracellular
Cell type enhanced (Macrophages, Kupffer cells, granulocytes, T-cells, NK-cells)
Low immune cell specificity
Cell line enhanced (HEL, HL-60, HMC-1, Karpas-707, MOLT-4, THP-1, U-937)
Interacts with SLA. Interacts with CBLB (By similarity). Interacts with GRB2 (PubMed:7706237). Interacts with SHB (PubMed:12084069). Interacts with PRAM1 (PubMed:11301322). Interacts (via SH2 domain) with CD6 (via tyrosine phosphorylated C-terminus) (PubMed:16914752, 24584089). Interacts with FYB1 and the phosphorylated form of FYB2 (PubMed:27335501).
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For Research Use Only. Not For Clinical Use.