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LDHA
Catalytic activity: (S)-lactate + NAD+ = H+ + NADH + pyruvate
Protein class
Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Basal keratinocytes, Basal respiratory cells, Extravillous trophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homotetramer (PubMed:11276087). Interacts with PTEN upstream reading frame protein MP31 (PubMed:33406399). Interacts with folliculin FLCN; the interaction is direct and inhibits enzymatic activity (PubMed:34381247).
Molecular function
Oxidoreductase
More Types Infomation
- Recombinant Mouse Anti-LDHA Monoclonal Antibody (20-179) (MRO-0921-CN)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: FC, ICC/IF, IHC-P, WB
-
- Species Reactivity: Human
- Application: ELISA, WB
- Mouse Anti-LDHA Recombinant Antibody (clone 8C6) (MOB-1952z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, IP
- Rabbit Anti-LDHA Polyclonal Antibody (MRO-2009-CN) (MRO-2009-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, FC
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF, IP
- Recombinant Mouse Anti-LDHA Antibody (VS-0923-FY106) (VS-0923-FY106)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
-
- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP, FC
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For Research Use Only. Not For Clinical Use.