Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins
Intracellular
Cell type enhanced (Proximal tubular cells, Distal tubular cells, Cardiomyocytes, Cytotrophoblasts, Syncytiotrophoblasts)
Low immune cell specificity
Cell line enhanced (RPTEC TERT1)
Homotetramer (PubMed:11276087). Interacts with PTEN upstream reading frame protein MP31; the interaction leads to inhibition of mitochondrial lactate dehydrogenase activity, preventing conversion of lactate to pyruvate in mitochondria (PubMed:33406399).
Oxidoreductase
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For Research Use Only. Not For Clinical Use.