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LGMN
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Hofbauer cells, Syncytiotrophoblasts, Macrophages)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Cell line enhanced (RPMI-8226, U-266/70)
Interaction
Homodimer before autocatalytic removal of the propeptide (By similarity). Monomer after autocatalytic processing. May interact with integrins.
Molecular function
Hydrolase, Protease, Thiol protease
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.