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LRRN2
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Excitatory neurons, Horizontal cells, Inhibitory neurons, Oligodendrocyte precursor cells, Astrocytes, Distal enterocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HEL, NTERA-2, RPMI-8226, SuSa, T-47d)
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.