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LSP1

This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (monocytes, Langerhans cells, Hofbauer cells, NK-cells, Plasma cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Daudi, HDLM-2, Karpas-707, RPMI-8226, U-937)

Interaction

Binds actin.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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