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LYVE1

LYVE1 is a type I integral membrane glycoprotein. It acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis.
Protein class

Plasma proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Hofbauer cells, Kupffer cells, Hepatic stellate cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (HUVEC TERT2)

Interaction

Homodimer; disulfide-linked. Interacts with PDGFB and IGFBP3. Forms a transient ternary complex with PDGFB and PDGFRB in TGN (By similarity).

Molecular function

Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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