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MACROD2

The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage.
Protein class

Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Excitatory neurons, Oligodendrocyte precursor cells, Astrocytes, Oligodendrocytes)

Immune cell specificity

Group enriched (naive B-cell, memory B-cell, neutrophil)

Cell line specificity

Cell line enhanced (EFO-21, Karpas-707, RT4, SCLC-21H)

Interaction

Interacts with ADP-ribosylated PARP1.

Molecular function

Hydrolase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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