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MAP1A
structural protein involved in the filamentous cross-bridging between microtubules and other cytoskeletal elements; may play a role in stabilizing the mature neuronal cytoskeleton [RGD, Feb 2006]
Protein class
FDA approved drug targets, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Horizontal cells, dendritic cells, Peritubular cells)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Cell line enhanced (ASC diff, BJ hTERT+, fHDF/TERT166, hTEC/SVTERT24-B, U-87 MG)
Interaction
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts with TIAM2. Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG4. Binds to CSNK1D (By similarity). MAP1 light chain LC2: Interacts with ELAVL4 (By similarity).
More Types Infomation
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- Species Reactivity: Rat
- Application: IHC-Fr, WB
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For Research Use Only. Not For Clinical Use.