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MARCKS
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Immune cell enhanced (neutrophil, intermediate monocyte)
Cell line specificity
Cell line enhanced (AF22, TIME)
Molecular function
Actin-binding, Calmodulin-binding
More Types Infomation
- Rabbit Anti-MARCKS (p Ser156) Antibody (MOB-060CQ)
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- Species Reactivity: Human, Mouse, Rat, Bovine, Chicken, Xenopus, Zebrafish
- Type: Rabbit IgG
- Application: WB
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- Species Reactivity: Human
- Application: ICC/IF, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC, ELISA
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: FC, ICC, IHC-P, WB
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For Research Use Only. Not For Clinical Use.