Disease related genes, Human disease related genes
Membrane
Cell type enhanced (Spermatocytes, Late spermatids, Early spermatids, Horizontal cells, Spermatogonia)
Not detected in immune cells
Not detected
Homotetramer (PubMed:24120416). Homooctamer formed by head-to-head interaction between homotetramers from adjoining membranes. Interacts with CALM; one CALM molecule interacts with the cytoplasmic domains of two aquaporins, leading to channel closure (By similarity). Interacts (via C-terminus) with BFSP1 (via C-terminus) in aged lens fiber cells (By similarity).
Eye lens protein
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For Research Use Only. Not For Clinical Use.