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MS4A12
The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Distal enterocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (RH-30)
Molecular function
Receptor
More Types Infomation
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- Species Reactivity: Human
- Application: IHC-Fr, WB
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For Research Use Only. Not For Clinical Use.