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MUM1

MUM1 (Melanoma Associated Antigen (Mutated) 1) is a Protein Coding gene. Diseases associated with MUM1 include Melanoma. Among its related pathways are DNA Damage. Gene Ontology (GO) annotations related to this gene include nucleosome binding. An important paralog of this gene is MUM1L1.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Cardiomyocytes, Extravillous trophoblasts, Adipocytes, Cytotrophoblasts, Hofbauer cells, Fibroblasts, Syncytiotrophoblasts, Smooth muscle cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with the BATF-JUNB heterodimer. Interacts with BATF (via bZIP domain); the interaction is direct (By similarity). Interacts with SPIB and DEF6. Directly interacts with NLRP3 in the nucleus of Th2 cells; this interaction enhances IRF4 ability to bind to the IL4 promoter and is required for optimal IRF4-dependent IL4 transcription (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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