Loading...
MXD3
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Erythroid cells, Granulosa cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (HDLM-2)
Interaction
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with SIN3A AND SIN3B. Interacts with RNF17 (By similarity).
Molecular function
DNA-binding, Repressor
More Types Infomation
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC-P, FC
- Mouse Anti-MXD3 Recombinant Antibody (MOB-4020z) (MOB-4020z)
-
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, ICC
- Recombinant Anti-Human MXD3 Antibody scFv Fragment (MOB-4020z-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, FC, FuncS
- Recombinant Anti-Human MXD3 Antibody Fab Fragment (MOB-4020z-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, IP, FuncS
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.