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MYF6

The protein encoded by this gene is a probable basic helix-loop-helix (bHLH) DNA binding protein involved in muscle differentiation. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of autosomal dominant centronuclear myopathy (ADCNM).
Protein class

Human disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Skeletal myocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (LHCN-M2)

Interaction

Efficient DNA binding requires dimerization with another bHLH protein. Interacts with CSRP3.

Molecular function

Developmental protein, DNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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