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N4BP1

Acts as a key negative regulator of select cytokine and chemokine responses elicited by TRIF-independent Toll-like receptors (TLRs), thereby limiting inflammatory cytokine responses to minor insults.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Alveolar cells type 1, Glandular and luminal cells)

Immune cell specificity

Immune cell enriched (neutrophil)

Cell line specificity

Low cell line specificity

Interaction

Interacts with NEDD4. Interacts with ITCH (via WW domain 2).

Molecular function

Hydrolase, Nuclease, RNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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