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NAGA

NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).
Protein class

Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Hofbauer cells, monocytes, Extravillous trophoblasts, Kupffer cells)

Immune cell specificity

Group enriched (non-classical monocyte, intermediate monocyte, classical monocyte, myeloid DC, plasmacytoid DC)

Cell line specificity

Cell line enhanced (HMC-1)

Interaction

Homodimer.

Molecular function

Glycosidase, Hydrolase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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