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NARFL
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
Predicted location
Intracellular
Single cell type specificity
Group enriched (Cytotrophoblasts, Hofbauer cells, Syncytiotrophoblasts, Cardiomyocytes, Extravillous trophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (REH)
Interaction
External component of the CIA complex (PubMed:22678361, PubMed:22678362, PubMed:23585563). In the CIA complex, interacts directly with CIAO1 and MMS19 (PubMed:23585563).
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, IF, IP
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For Research Use Only. Not For Clinical Use.