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NDRG2

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Sertoli cells, Muller glia cells, Distal tubular cells, Astrocytes)

Immune cell specificity

Immune cell enriched (myeloid DC)

Cell line specificity

Cell line enhanced (Hep G2, HMC-1)

Interaction

Interacts with CTNNB1.

Molecular function

Developmental protein

More Types Infomation

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