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NEUROG3
The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
Protein class
Disease related genes, Human disease related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Cardiomyocytes, Enteroendocrine cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (THP-1)
Interaction
Efficient DNA binding requires dimerization with another bHLH protein. Interacts with ATOH8.
Molecular function
Activator, Developmental protein, DNA-binding
More Types Infomation
-
- Species Reactivity: Human
- Application: WB
- Mouse Anti-NEUROG3 Recombinant Antibody (VS3-WK1227) (VS3-WK1227)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.