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NLGN3
NLGN3 (Neuroligin 3) is a Protein Coding gene. This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Diseases associated with NLGN3 include Autism X-Linked 1 and Asperger Syndrome, X-Linked 1.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Oligodendrocytes, Astrocytes, Peritubular cells, Inhibitory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, NTERA-2, SH-SY5Y)
Interaction
Interacts with NRXN1, NRXN2 and NRXN3. Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3) (By similarity). Homodimer, and heterodimer with NLGN1 and NLGN2 (By similarity).
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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- Species Reactivity: Human
- Type: IgG
- Application: FC
- Rabbit Anti-NLGN3 Recombinant Antibody (VS-0522-LC120) (VS-0522-LC120)
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- Species Reactivity: Rat, Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC
- Human Anti-NLGN3 Recombinant Antibody (VS-0522-LC119) (VS-0522-LC119)
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- Species Reactivity: Rat, Human, Mouse
- Type: Human IgG1
- Application: WB, IF, IHC
- Rat Anti-NLGN3 Recombinant Antibody (VS-0522-LC118) (VS-0522-LC118)
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- Species Reactivity: Rat, Human, Mouse
- Type: Rat IgG2b
- Application: WB, IF, IHC
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For Research Use Only. Not For Clinical Use.