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NOLC1

Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Heterodimer; heterodimerizes with TCOF1 following monoubiquitination (PubMed:26399832). Interacts with RNA polymerase I 194 kDa subunit (RPA194) and with casein kinase-II (PubMed:10567578). Interacts with DKC1/NAP57, NOP58 and fibrillarin (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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