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NOX1

NOX1 encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide.
Protein class

Disease related genes, Plasma proteins, Potential drug targets, Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Undifferentiated cells, Distal enterocytes, Paneth cells, Intestinal goblet cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (CACO-2, OE19)

Interaction

NOX1, NOXA1, NOXO1, RAC1 and CYBA forms a functional multimeric complex supporting reactive oxygen species (ROS) production. Interacts with NOXA1 and NOXO1.

Molecular function

Ion channel, Oxidoreductase, Voltage-gated channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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