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NSG1
NSG1 (Neuron Specific Gene Family Member 1) is a Protein Coding gene. GO annotations related to this gene include clathrin light chain binding. An important paralog of this gene is HMP19.
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Melanocytes, Bipolar cells, Suprabasal keratinocytes, Granulosa cells, Cytotrophoblasts)
Immune cell specificity
Group enriched (MAIT T-cell, gdT-cell, memory CD4 T-cell, memory CD8 T-cell, naive CD8 T-cell)
Cell line specificity
Cell line enhanced (HAP1, SCLC-21H, SH-SY5Y, SK-MEL-30, TIME, U-698)
Interaction
Forms a complex with GRIP1, GRIA2 and STX12 through direct interaction with GRIP1; controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting. Interacts with STX12 (By similarity). Interacts with APP; could regulate APP processing (By similarity). Interacts with FAM171A1 (PubMed:30312582).
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.