Loading...
NUCB1
Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis (By similarity).
Protein class
Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Proximal enterocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts (via GBA motif) with guanine nucleotide-binding protein G(i) alpha subunits GNAI1, GNAI2 and GNAI3 with higher affinity for GNAI1 and GNAI3 than for GNAI2. Preferentially interacts with inactive rather than active GNAI3. Interaction with GNAI3 is inhibited when NUCB1 binds calcium, probably due to a conformational change which renders the GBA motif inaccessible.
Molecular function
DNA-binding, Guanine-nucleotide releasing factor
More Types Infomation
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, ICC, IF, IHC
-
- Species Reactivity: Human
- Application: IHC-P, WB
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP
- Chicken Anti-NUCB1 Polyclonal IgY (BRD-0400MZ)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.