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OAS3

This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
Protein class

Enzymes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (monocytes)

Immune cell specificity

Immune cell enhanced (non-classical monocyte)

Cell line specificity

Group enriched (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, GAMG, RT4)

Interaction

Monomer.

Molecular function

Nucleotidyltransferase, RNA-binding, Transferase

More Types Infomation

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