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OLFM4

This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion.
Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Undifferentiated cells, Urothelial cells, Pancreatic endocrine cells, Exocrine glandular cells, Intestinal goblet cells, Paneth cells, Ductal cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BEWO, BJ hTERT+, HaCaT, OE19, RPMI-8226)

Interaction

Homomultimer; disulfide-linked. Interacts with NDUFA13. Interacts with cell surface lectins (locutions ricinus communis agglutinin I, concanavalin-A and wheat germ agglutinin) and cadherin.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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