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OPRD1
Enables G protein-coupled enkephalin receptor activity. Involved in several processes, including G protein-coupled opioid receptor signaling pathway; cellular response to hypoxia; and positive regulation of peptidyl-serine phosphorylation. Is intrinsic component of plasma membrane.
Protein class
FDA approved drug targets, G-protein coupled receptors, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Inhibitory neurons, Excitatory neurons, Bipolar cells, Skeletal myocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (RH-30, SCLC-21H, SH-SY5Y, WM-115)
Interaction
May form homooligomers. Forms a heterodimer with OPRM1 (By similarity). Interacts with GPRASP1 (PubMed:12142540, PubMed:15086532). Interacts with RTP4; the interaction promotes cell surface localization of the OPRD1-OPRM1 heterodimer (By similarity).
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, IP
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, FC
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, FC
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, FC
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.