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P2RX5

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). [provided by RefSeq, Mar 2011]
Protein class

Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (B-cells, Plasma cells)

Immune cell specificity

Group enriched (naive B-cell, memory B-cell)

Cell line specificity

Cell line enhanced (Daudi, Karpas-707, RPMI-8226, U-698)

Interaction

Functional P2XRs are organized as homomeric and heteromeric trimers.

Molecular function

Ion channel, Ligand-gated ion channel, Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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