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PBX4
This gene encodes a member of the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
Protein class
Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (T-cells, Spermatocytes, Plasma cells, Gastric mucus-secreting cells, dendritic cells)
Immune cell specificity
Group enriched (T-reg, memory CD8 T-cell, MAIT T-cell, gdT-cell, naive CD4 T-cell, memory CD4 T-cell, naive CD8 T-cell)
Cell line specificity
Cell line enhanced (A-431, RT4)
Molecular function
Activator, DNA-binding
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.