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PCDH1

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq, Jul 2008]
Protein class

Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Distal enterocytes, Pancreatic endocrine cells, Adipocytes, Urothelial cells, Exocrine glandular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CAPAN-2, HaCaT, HUVEC TERT2, OE19, RT4, TIME, WM-115)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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