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PCDH10

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Excitatory neurons, Oligodendrocytes, Astrocytes, Inhibitory neurons, Oligodendrocyte precursor cells, Glandular and luminal cells, Endometrial ciliated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (hTERT-RPE1, HUVEC TERT2, MOLT-4, TIME, U-138 MG, U-251 MG)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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