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PCK2

This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of guanosine triphosphate (GTP). A cytosolic form of this protein is encoded by a different gene and is the key enzyme of gluconeogenesis in the liver. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2014]
Protein class

Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Group enriched (Proximal enterocytes, Hepatocytes, Proximal tubular cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HHSteC, hTCEpi, SK-MEL-30)

Interaction

Monomer.

Molecular function

Decarboxylase, Lyase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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