Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Intracellular
Cell type enhanced (Excitatory neurons, Inhibitory neurons, Early spermatids)
Low immune cell specificity
Low cell line specificity
Homodimer. Interacts with the pyruvate dehydrogenase complex subunit DLAT, and is part of the multimeric pyruvate dehydrogenase complex that contains multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (DLAT, E2) and lipoamide dehydrogenase (DLD, E3).
Kinase, Transferase
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For Research Use Only. Not For Clinical Use.