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PIAS4
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids, Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with AR, AXIN1, GATA2, LEF1, TP53 and STAT1 (IFNG-induced) (PubMed:11248056, PubMed:11388671, PubMed:11439351, PubMed:12223491, PubMed:12750312). Interacts with TICAM1 (PubMed:15251447). Interacts with KLF8; the interaction results in SUMO ligation and repression of KLF8 transcriptional activity and of its cell cycle progression into G(1) phase (PubMed:16617055). Interacts with MTA1 (PubMed:21965678). Interacts with PRDM1/Blimp-1 (PubMed:28842558). Interacts with TRIM32 upon treatment with UVB and TNF-alpha (By similarity).
Molecular function
DNA-binding, Repressor, Transferase
More Types Infomation
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- Species Reactivity: Human
- Application: ELISA, ICC, WB
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For Research Use Only. Not For Clinical Use.