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PILRA
The antibody is against FDF03 which is immunoregulatory receptor on myeloid cell, also known as Paired Immunoglobulin-Like type 2 Receptor (PILR). And it is used for the treatment of cancer.
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Macrophages, Kupffer cells, Hofbauer cells, monocytes, Langerhans cells, Leydig cells)
Immune cell specificity
Immune cell enhanced (neutrophil, non-classical monocyte)
Cell line specificity
Cell line enhanced (ASC diff, HMC-1, NB-4)
Interaction
Monomer. Interacts with PTPN6/SHP-1 and PTPN11/SHP-2 upon tyrosine phosphorylation. (Microbial infection) Interacts with herpes simplex virus 1 glycoprotein B.
Molecular function
Receptor
More Types Infomation
- Human Anti-PILRA Antibody, mRNA (TAB-744CL-mRNA)
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- Species Reactivity: Human
- Anti-Human PILRA Therapeutical Antibody (TAB-744CL)
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- Species Reactivity: Human
- Type: Antibody
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
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For Research Use Only. Not For Clinical Use.