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PINK1
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Low cell line specificity
Interaction
Interacts with PRKN (PubMed:20798600, PubMed:19966284). Interacts with FBXO7 (PubMed:23933751). Forms a complex with PRKN and PARK7 (PubMed:19229105). Interacts with NENF (PubMed:31536960).
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
- Rabbit Anti-PINK1 Polyclonal Antibody (MRO-2122-CN) (MRO-2122-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC
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- Species Reactivity: Human
- Application: ELISA, ICC/IF, WB
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC
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For Research Use Only. Not For Clinical Use.