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POLR2L
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
Protein class
Metabolic proteins, Plasma proteins, RNA polymerase related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells, Hepatocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (A549, PC-3)
Interaction
Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
More Types Infomation
- Recombinant Anti-Human POLR2L Antibody (MOB-1836z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, FuncS
- Recombinant Anti-Human POLR2L Antibody scFv Fragment (MOB-1836z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IP, FuncS
- Recombinant Anti-Human POLR2L Antibody Fab Fragment (MOB-1836z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: FC, IP, FuncS
- Chicken Anti-POLR2L Polyclonal IgY (BRD-0424MZ)
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- Species Reactivity: Human, Mouse
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.