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POLR3F
The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB (TFIIIB). Unlike most of the other RNA Pol III subunits, the encoded protein is unique to this polymerase. Alternative splicing results in multiple transcript variants.
Protein class
Metabolic proteins, RNA polymerase related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits. RPC3/POLR3C, RPC6/POLR3F and RPC7/POLR3G form a Pol III subcomplex (By similarity). Directly interacts with POLR3C (PubMed:21358628). Interacts with TBP and TFIIIB90 and GTF3C4 (By similarity) (PubMed:10523658). Interacts with MAF1 (PubMed:18377933).
Molecular function
DNA-binding
More Types Infomation
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Recombinant Anti-Human POLR3F Antibody scFv Fragment (MOB-3513z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: Neut, IF, FuncS
- Recombinant Anti-Human POLR3F Antibody Fab Fragment (MOB-3513z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, FuncS
-
- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.