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PPARGC1B
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor.
Protein class
Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cone photoreceptor cells, Bipolar cells, Rod photoreceptor cells)
Immune cell specificity
Immune cell enhanced (non-classical monocyte)
Cell line specificity
Low cell line specificity
Interaction
Interacts with hepatocyte nuclear factor 4-alpha/HNF4A, Sterol regulatory binding transcription factor 1/SREBF1, PPAR-alpha/PPARA, thyroid hormone receptor beta/THRB and host cell factor/HCFC1. Interacts with estrogen-related receptor gamma/ESRRG and alpha/ESRRA. Interacts with PRDM16 (By similarity). Interacts with estrogen receptor alpha/ESR1.
Molecular function
Activator, RNA-binding
More Types Infomation
Related Signaling Pathways
PPAR Signaling Pathway
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, ICC/IF, FC, IP
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IP, FC
- Recombinant Anti-Human PGC-1 beta Antibody (MOB-0311MC)
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- Species Reactivity: Human
- Application: ELISA, FACS, WB
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- Derivation: Rabbit
- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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- Species Reactivity: Human
- Type: Mouse IgG2a
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- Type: Mouse IgG1
- Application: FC
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For Research Use Only. Not For Clinical Use.