Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts with phosphorylated CDC5L, SF3B1 and MELK. Interacts with EED, in a nucleic acid-stimulated manner. Part of a complex consisting of PPP1R8, EED, HDAC2 and PP-1. Part of the spliceosome. Interacts with PPP1CA, PPP1CB and PPP1CC.
DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein phosphatase inhibitor, Repressor, RNA-binding
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For Research Use Only. Not For Clinical Use.